September 15 - Peter Arbues, is assassinated while praying in the cathedral at Saragossa, Spain and he died on September 17. He had been appointed Inquisitor of Aragon by the Inquisitor General, Tomás de Torquemada, in the campaign against heresy and crypto-Judaism.
December 5 - Pope Innocent VIII gives the inquisition a mission to hunt heretics and witches in Germany with the lead of Heinrich Kramer and Jacob Sprenger.